Compatibility of vitamin D3 and omega-3 with other vitamins and medications

Compatibility of vitamin D3 and omega-3 with other vitamins and medications

For supplements and vitamins to do the most good for your health, it is important to know about their compatibility.

After all, some vitamins cannot be taken together and can interfere with each other’s absorption, reduce the effect to zero and even cause side effects.

We’ve compiled the best and worst combinations of Omega-3 and Vitamin D3 with other vitamins and medications.

Let’s sort out who they’re friends with and who they’re better off staying away from.

Vitamin D3 and Omega-3 work very harmoniously, and they don’t compete with each other.

Since Vitamin D3 is a fat-soluble vitamin, Omega-3 improves its absorption.

Moreover, the combined use of Vitamin D3 and Omega-3 is determined by nature itself.

For example, Omega-3 from cod contains natural vitamin D – it is synthesized in the liver of fish during life.

What Omega-3 should not be taken with

What Omega-3 should not be taken with

  1. Aspirin and other anticoagulants Omega-3 is a blood thinner.

    Therefore, taking it together with blood thinners may provoke bleeding.
  2. Medications for high blood pressure Omega-3 reduces the effectiveness of such medications and may cause blood pressure to be too low.

    Consult your doctor before taking them along with Omega-3.
  3. Birth control pills Omega-3s help lower cholesterol levels.

    If taken together with contraceptives, then the effectiveness of Omega-3 will be minimal.⠀
  4. Calcium, Magnesium, Iron, Zinc, Selenium, Copper, Chromium

    With simultaneous consumption, the absorption of Omega-3 in the gastrointestinal tract may slow down.

    We recommend splitting your intake at least two hours apart.
What you can take Omega-3 with

What can you take Omega-3 with

  1. Fat Soluble Vitamins A, D, E
  1. Coenzyme Q10 mitochondrial support and lecithin
  2. B vitamins: B2, B6, folic acid, B12

    Effectively interact with Omega-3 and improve cognitive abilities.
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Who is not a friend of Vitamin D

Who is not a friend of vitamin D

  1. Vitamin E

    In moderate doses, this vitamin is a useful supplement to D3.

    But in high doses, it can block the absorption of vitamin D.

    It is important to remember that some of the omega-3 producers add Vitamin E to their products because of the poor quality of their raw materials (fat from small fish). In such cases, Vitamin D has no useful properties.
  2. Iron supplements

    Iron preparations and Vitamin D3 interfere with each other.

    Therefore, it is necessary to separate the intake by 2 hours.
  3. Drugs against epilepsy, anti-tuberculosis drugs and sleeping pills

    The absorption of both vitamin D and these drugs is impaired when taken at the same time.
  4. Magnesium antacids.

    Concomitant use of vitamin D and medications for the treatment of gastrointestinal diseases (antacids).

    May result in elevated blood magnesium levels.
  5. Drugs to normalize calcium levels and diuretics

    When taking simultaneously, Vitamin D3 neutralizes the effect of these drugs and may provoke high levels of calcium in the blood.
Who is Vitamin D's friend

Who is vitamin D’s friend

Who is vitamin D friends with?

  1. Calcium, Phosphorus, Magnesium

    Vitamin D3 is involved in the exchange of these minerals and enhances their absorption. Therefore, simultaneous intake has a positive effect on the health of bones, teeth, and nails.

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  1. Vitamin K2

    If Vitamin D3 promotes the absorption of calcium in the body, then Vitamin K2 enhances its action – directs calcium to bones, teeth, nails and prevents calcium deposition in blood vessels, arteries, and organs.

    At high dosages of vitamin D (more than 5000 IU), it is recommended to take it in combination with K2.

    It is especially important to take Vitamin D3 along with K2 for those who:
    1. Predisposition to the formation of stones and sand in the organs
    2. Cardiovascular disease
    3. Severe fractures, joint pain
    4. Menopause
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  1. B vitamins: B1, B2, B5, B6
Life Extension BioActive Complete B-Complex (60 Vegetarian Capsules)

Life Extension BioActive Complete B-Complex (60 Vegetarian Capsules)

BioActive Complete B-Complex is a complete supplement for vitamin B benefits. It is packed with the biologically active forms of vitamin B6, B12, niacin, biotin, 5-MTHF folate to support energy production and metabolic processes. BioActive Complete B-Complex, 60 vegetarian capsules


  1. Vitamins A, C

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